FAQs
英國BHM®隱形口罩噴霧劑專利配方有什麼獨特之處?
獨特的專利配方 Norizite™ 具有增強的噴霧粘附特性,更有效覆蓋鼻腔內的面積,並延長噴霧劑在鼻腔中的停留時間。噴霧劑的噴嘴經由精心設計,噴嘴採用“霧化”而不是“噴射”。 伯明翰大學的研究證實,Norizite®的配方中的凝膠混合物相比沒有凝膠成份的,可增強粘附能力高達六倍,並有抑制病毒作用。
BHM® Norizite™ 抗病毒鼻腔噴霧劑,以物理學抑制病毒。如 SARS-CoV-2。並能將其病毒從鼻子中自然排出。 使使用者能夠有足夠的額外保護,能安心進行日常活動。
在科學角度中如何証明噴霧劑可抑制病毒呢?
噴霧含有天然成分卡拉膠,已被證明具有抑制病毒特性。 研究表明,卡拉膠可防止病毒粒與體內細胞結合並入侵身體細胞,引起感染。
伯明翰大學實驗室測試指出,Norizite™ 可以防止培養中的細胞感染 SARS-CoV-2。 研究證實,當病毒遇上卡拉膠與結冷膠混合物時,可完全抑制 SARS-CoV-2 感染長達 48 小時。 伯明翰大學的後續實驗室研究表明,Norizite™ 在細胞培養中也能有效對抗 SARS-CoV-2 的兩種傳染性變體。 伯明翰生物技術公司計劃測試該產品對其他 SARS-CoV-2 變體以及其他引起普通感冒和流感的病毒(包括鼻病毒、流感病毒和呼吸道合胞病毒)的功效。
BHM® 隱形口罩噴霧劑安全嗎?
BHM® 隱形口罩噴霧劑含有 Norizite™,這是一種獲得專利的天然成分混合物,包括角卡拉膠和結冷膠。這些都是大碳水化合物聚合物,這意味著它們不太可能被身體吸收。
卡拉膠有助於減緩或預防鼻腔內的病毒感染。它無毒性,不會在人類細胞系中產生炎症反應或負面影響,並且對細胞培養中生長的細胞的活力沒有負面影響。美國食品和藥物管理局(GRAS),世界衛生組織的食品添加劑聯合專家委員會 (JECFA) 和歐洲食品安全局也一致認為它對普遍的人是安全的。
結冷膠是一種膠凝劑,最初被批准為食品添加劑,隨後被包括美國和歐盟在內的許多監管機構批准用於其他非食品、化妝品和藥物用途。歐盟委員會監管委員會報告說,結冷膠是完全安全的,從動物和人類的試驗中可以看出,當大量使用結冷膠時沒有不良反應。結冷膠被身體排出而不被吸收的發現進一步支持了這一點。
噴鼻劑進入人體後會怎樣排出體外呢?
噴霧劑會包裹著病毒粒通過人體的自然排出體外。
這些包括通過纖毛去除(去除鼻子內物質的“掃帚狀”的纖毛),通過打噴嚏或咳嗽、如果由吞嚥則通過糞便排泄。
噴霧劑如何留在鼻子裡? 不會滴出來嗎?
產品中的多醣凝膠 (Polysaccharide gel) 擁有粘附特性,它能夠粘在鼻腔細胞頂部的粘液層上。
英國伯明翰大學的研究人員仔細評估了配方的粘度,以確認當按指示使用噴霧劑時,噴霧劑會粘附在鼻子內接近垂直的表面上,而不會滴出。
如果我使用噴霧劑,我還需要戴口罩嗎? 鼻噴霧劑可以替代疫苗接種嗎?
噴霧劑是方便我們在保持社交距離和常規衛生措施提供的額外保護層。它不能替代戴口罩和不能替代疫苗接種。
噴霧劑會幫助治療已經感染的人嗎?
噴霧劑並不是藥物,不會緩解症狀或治療疾病。噴霧劑是在鼻腔中形成一道屏障,額外提供的一層保護,防止病毒進入人體。
使用說明及儲存方法
使用說明
成人及12歲以上小孩適用,12歲以下請查詢醫生專業意見。
此產品亦適合在懷孕期間使用。
每個鼻孔噴 2-3次,每天最多4次,全天保護(不要超過推薦用量)。
1. 取下瓶蓋,保持瓶子直立,噴到空氣中,直至霧化均勻釋放。
2. 小心地將噴嘴置於鼻孔口,一邊鼻孔噴2-3次。
3. 另一側鼻孔重複。
4. 使用後立即合上蓋子。
儲存方法
在2°C至30°C之間的環境下直立存放。
遠離陽光直射和熱源。
不要讓瓶子保持打開狀態。
FAQs
What is unique about the BHM° NoriZite Nasal Spray?
It is specially formulated to "spray" rather than" jet when applied, for significantly greater coverage in the nasal passages.
How is it scientifically proven that sprays can inhibit viruses?
The spray contains the natural ingredient Carrageenan, which has been shown to have virus-inhibiting properties. Studies have shown that carrageenan prevents virus particles from binding to and invading cells in the body, causing infection.
University of Birmingham laboratory tests indicate that Norizite™ prevents SARS-CoV-2 infection of cells in culture. Studies have confirmed that when the virus encounters a mixture of carrageenan and gellan gum, it completely inhibits SARS-CoV-2 infection for up to 48 hours. Follow-up laboratory studies at the University of Birmingham showed that Norizite™ is also effective against two infectious variants of SARS-CoV-2 in cell culture. Birmingham Biotech plans to test the product's efficacy against other SARS-CoV-2 variants and other viruses that cause the common cold and flu, including rhinovirus, influenza virus and respiratory syncytial virus.
Is BHM® Invisible Mask Spray Safe?
>BHM® Invisible Mask Spray contains Norizite™, a patented blend of natural ingredients including carrageenan and gellan gum. These are large carbohydrate polymers, which means they are less likely to be absorbed by the body.
Carrageenan helps slow or prevent viral infections in the nasal passages. It is non-toxic, does not produce inflammatory responses or negative effects in human cell lines, and has no negative effects on the viability of cells grown in cell culture. The US Food and Drug Administration (GRAS), the World Health Organization's Joint Expert Committee on Food Additives (JECFA) and the European Food Safety Authority also agree that it is safe for the average person.
Gellan gum is a gelling agent initially approved as a food additive and subsequently approved for other non-food, cosmetic and pharmaceutical uses by many regulatory agencies including the US and EU . The European Commission's Regulatory Commission reports that gellan gum is completely safe, with no adverse effects when used in large quantities as seen in animal and human trials. This is further supported by the finding that gellan gum is excreted by the body without being absorbed.
How will the nasal spray be excreted after entering the human body?
The spray encapsulates the virus particles through the body's natural excretion.
These include removal by cilia (the "broom-like" cilia that remove material from the nose), by sneezing or coughing, and by feces if swallowed.
How does the spray stay in the nose? Won't it drip out?
The polysaccharide gel in the product has adhesive properties, it sticks to the mucus layer on top of the nasal cells.
Researchers at the University of Birmingham, UK, carefully evaluated the viscosity of the formulation to confirm that when the spray was used as directed, it would stick to near-vertical surfaces inside the nose without dripping.
Do I still need to wear a mask if I use the spray? Can nasal sprays replace vaccinations?
these are an extra layer of protection that we provide while maintaining social distancing and regular hygiene practices. It is not a substitute for wearing a mask and it is not a substitute for vaccinations.
Will the spray help treat someone who is already infected?
Sprays are not medicines and do not relieve symptoms or treat disease. The spray forms a barrier in the nasal cavity, providing an extra layer of protection from viruses entering the body.
Instructions for use and storage methods
Directions for Use For all ages over 12 years, under 12 years consult any pediatrician in person. Suitabte for use during pregnancy. Apply 2-3 sprays up to 4 times a day for a full day protection. (Do not exceed recommended application). 1. Remove the cap and, while holding the bottle upright, spray into the air until a uniform mist is released. 2. Insert the nozzle carefully into one nostril, spray 2-3 pumps into one nostril while holding the other nostrill closed. 3. Repeat with the opposite nostril. 4. Close the cap immediately after use.
到底英國BHM®隱形口罩噴霧劑如何有效抑制病毒?有什麼科學證據呢?一齊聽聽研發的生物科學和醫療保健技術教授 Liam Grover 親身說說How does the British BHM® invisible mask spray effectively inhibit the virus? What scientific evidence is there?
與市場上的其他同類產品相比,英國BHM®隱形口罩噴霧劑專利配方有什麼獨特之處?Compared with other similar products on the market, what is unique about the patented formula of British BHM® Invisible Mask Spray?
參巧文獻 References
{1} Moakes R, Davies S, Stamataki Z, Grover L. Formulation of a Composite Nasal Spray Enabling Enhanced Surface Coverage and Prophylaxis of SARS-COV-2. Advanced Materials. 2021;33(26):2008304.
{2} Leibbrandt A, Meier C, König-Schuster M, Weinmüllner R, Kalthoff D, Pflugfelder B, Graf P, Frank-Gehrke B, Beer M, Fazekas T, Unger H, Prieschl-Grassauer E, Grassauer A. Iota-carrageenan is a potent inhibitor of influenza A virus infection. PLoS One. 2010;5(12):e14320
{3} Grassauer A, Weinmuellner R, Meier C, Pretsch A, Prieschl-Grassauer E, Unger H. Iota-Carrageenan is a potent inhibitor of rhinovirus infection. Virology Journal. 2008;5:107
{4} McKim J, Baas H, Rice G, Willoughby J, Weiner M, Blakemore W. Effects of carrageenan on cell permeability, cytotoxicity, and cytokine gene expression in human intestinal and hepatic cell lines. Food and Chemical Toxicology. 2016;96:1-10.
{5} Younes M, Aggett P, Aguilar F, Crebelli R, Filipic M, Frutos M et al. Re-evaluation of gellan gum (E 418) as food additive. EFSA Journal. 2018;16(6).
{6} Younes M, Aggett P, Aguilar F, Crebelli R, Filipič M, Frutos M et al. Re-evaluation of carrageenan (E 407) and processed Eucheuma seaweed (E 407a) as food additives. EFSA Journal. 2018;16(4).